Lyme Study Consent Agreement

Overview

A two-week supply of CelWel will be provided to you at no cost.

CelWel is an oral supplement containing extracts of Tinospora Cordifolia and Piper Pigrum, as well as a very low concentration of Thimerosal.

The CelWel supplement is a viable and safe option for reducing the severity of symptoms in patients with Long COVID [2] and possibly chronic Lyme disease.

Primary Ingredients

T. cordifolia, one of the constituents of CelWel, has demonstrated anti-inflammatory activity by lowering pro-inflammatory cytokine levels (IL-1, TNF-alpha;, IL-6, and IL-17), the frequency of IL-17-producing T cells, and the production of chemokines (RANTES) [1]

Of note, there is a small amount of thimerosal presumably as an antimicrobial effect, keeping the solution sterile. According to the CDC, Thimerosal is a mercury-based preservative that has been used for decades in the United States in multi-dosevials (vials containing more than one dose) of medicines and vaccines. There is no evidence of harm caused by the low doses of thimerosal in vaccines, except for minor reactions like redness and swelling at the injection site. [3]

Study Protocol

The protocol involves completion of a pretest questionnaire. Click HERE to view screen captures of the questionnaire.

A link to the first Health Symptoms Questionnaire will be emailed to the email address entered at the start of this registration.

After completion of the first questionnaire, begin consuming CelWel.

Use the dropper to put 0.4ml of CelWel under your tongue. Try NOT to swallow for 15 seconds. Do NOT eat or drink for the next five minutes to maximize absorption.

On the 1st day: 0.4 mL approximately every 15 minutes the first hour, then approximately every hour until bed.

The 2nd and 3rd days: 0.4ml approximately every 3 hours.

Days 4 and beyond: approximately 4-6 times daily while awake until course is completed (2 weeks in the published study [2]).

According to the manufacturer, they suggest that you continue using CelWel, four times per day, for another two weeks or until you have used up your supply.

At the end of a 2-week course, we request completion of the 2nd survey. A link to the 2nd survey will be emailed to the email address that entered at the start of this registration.

CelWel's Effects for Some Subjects

Some subjects have found that they no longer need to take CelWel, ever. Some subjects only take CelWel if their symptoms recur. And some subjects like to continue taking CelWel on-going. Sometimes they even take more doses per day, every day. CelWel is perfectly safe to take, even up to ten or fifteen times per day, forever.

Footnotes

1. Sannegowda KM, Venkatesha SH, Moudgil KD (2015) Tinospora cordifolia inhibits autoimmune arthritis by regulating key immune mediators of inflammation and bone damage. Int J Immunopathol Pharmacol 28:521-531.

2. Sigamani A, Kumar SS, Naik KS (2023) Effects of a Natural Extract on Molecular Signature in Post-Acute Sequelae SARSCoV-2 (PASC) Infection: A Quasi-Experimental Study. Divers Equal Health Care. 20:11.

3. https://www.cdc.gov/vaccinesafety/concerns/thimerosal/index.html last accessed 11/12/23

Agreement to Participate in the Study

By signing this electronic form, I agree to proceed with this program and have had all of my questions adequately answered by my professional medical provider identified on the previous page of this form and/or one of my provider's associates.